Does increased nuchal translucency indicate a fetal abnormality? A retrospective study to clarify the clinical significance of nuchal translucency in Japan

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Fetal nuchal translucency scan in Nigeria

INTRODUCTION To evaluate the performance of first trimester nuchal translucency scan screening among pregnant women in Nigeria. METHODS A prospective observational and questionnaire based study involving 510 pregnant women between 11(+0) and 13(+6) weeks. Routine counselling and nuchal translucency measurement was conducted using the FMF, London guidelines. Chorionic villous sampling was done...

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Outcome of pregnancies with increased nuchal translucency

Methods A total of 1490 pregnant women were assessed for first trimester ultrasonography. They had routinely measured crown-rump length (CRL) and nuchal translucency (NT) for screening for Down syndrome between 11 and 14 weeks of gestation. Cases with a NT≥3 mm were counselled further regarding the risk of chromosomal abnormality and prenatal diagnosis by fetal karyotyping. A complete follow-up...

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Increased Nuchal Translucency and Pregnancy Outcome

BACKGROUND To study the outcome of cases with nuchal translucency (NT) ≥ 95th centile in the first trimester of pregnancy. METHODS This cross sectional study was performed at Iranian Fetal Medicine Foundation (FMF) between January 2009 and December 2011. Totally, 186 cases with NT≥ 95th centile who attended for the first trimester screening were studied. All cases with increased NT including ...

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Increased fetal nuchal translucency at 11-14 weeks.

Nuchal translucency (NT) is the sonographic appearance of a subcutaneous collection of fluid behind the fetal neck. The measurement of fetal NT thickness at the 11-14-week scan has been combined with maternal age to provide an effective method of screening for trisomy 21; for an invasive testing rate of 5%, about 75% of trisomic pregnancies can be identified. When maternal serum free-beta human...

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Pathophysiology of increased nuchal translucency: a review of the literature.

First-trimester nuchal translucency (NT) measurement is a widely used technique to determine the risk of fetal aneuploidy. The aim of this review was to explore the different hypotheses on the aetiology of increased NT. Using a computerized database (PubMed), articles on the aetiology of first-trimester NT were retrieved. Furthermore, the cited references of the studied articles were used to fi...

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ژورنال

عنوان ژورنال: Journal of Human Genetics

سال: 2008

ISSN: 1434-5161,1435-232X

DOI: 10.1007/s10038-008-0299-6